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Effect of Air Pollution on the Cognitive Function of Adolescents

Not Applicable
Completed
Conditions
Attention Impaired
Risk Behavior
Attention
Risk-Taking
Social Preferences
Decision Making
Interventions
Other: Purifying the air with a Pure Airbox device (Zonair 3D)
Other: Using a sham air purifier (same device without filters)
Registration Number
NCT03762239
Lead Sponsor
Barcelona Institute for Global Health
Brief Summary

Previous observational studies have reported an association between higher air pollution exposure and lower attention in children. With this project, the investigators aim to confirm this association in adolescents using an experimental design. In addition, the study will assess the relationship between air pollution exposure and individual preferences with respect to risk, time and social considerations. High school students in 3rd grade (ESO, 14-15 years of age) in different high schools in the Barcelona province (Spain) will be invited to participate. For each class in each high school, participating students will be randomly split into two equal-sized groups. Each group will be assigned to a different classroom where they will complete several activities during two hours, including an attention test (Flanker task) and a reduced version of the Global Preferences Survey. One of the classrooms will have an air purifier that will clean the air. The other classroom will have the same device but without the filters, so it will only re-circulate the air without cleaning it. Students will be masked to intervention allocation. The investigators hypothesize that students assigned to the clean air classroom will have better scores in the attention test, and that decision-making will also present differences in the two classrooms.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
2123
Inclusion Criteria
  • Students in the 3rd ESO course in participating high schools with signed informed consent
Exclusion Criteria
  • None

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Purified airPurifying the air with a Pure Airbox device (Zonair 3D)Purifying the air with a Pure Airbox device (Zonair 3D). Use of air purifier (Pure Airbox, Zonair 3D) in the classroom 30 minutes before the participants enter the room and during the 2 hours of the experiment.
Normal airUsing a sham air purifier (same device without filters)Using a sham air purifier (same device without filters). Use of the same air purifier but without filters, so that it only recirculates the air without purifying it. Used for the same time period than the other arm.
Primary Outcome Measures
NameTimeMethod
Positive reciprocity scoreObtained from a test administered approximately 100 minutes after entering the classroom

Positive reciprocity = 0.4847038 × "Willingness to return favor" + 0.5152962 × "Size of gift", that follows the parameters of Falk et al (2018), where "Willingness to return favor" refers to the answer to the question on the willingness to return a favor, and "Size of gift" refers to the answer to the question on the reported size of the gift that would return to a stranger.

Trust scoreObtained from a test administered approximately 100 minutes after entering the classroom

Answer to the question "I assume that people have only the best intentions".

Combined patience scoreObtained from a test administered approximately 100 minutes after entering the classroom

Patience = 0.7115185 × "Time preference score" + 0.2884815 × "Self assessment of patience", that follows the parameters of Falk et al (2018), where the "Time preference score" is the final node in the time tree (see the online appendix of Falk et al (2018)), which is a value between 1 and 32, ranked by the level of patience, and the "Self assessment of patience" refers to the answer to the question on the self-assessment of patience (willingness to give up something today).

Altruism scoreObtained from a test administered approximately 100 minutes after entering the classroom

Altruism = 0.6350048 × "Willingness to give to good causes" + 0.3649952 × "Hypothetical donation", that follows the parameters of Falk et al (2018), where "Willingness to give to good causes" refers to the answer to the question on the willingness to give to good causes, and "Hypothetical donation" refers to the answer to the question on the size of the hypothetical donation one would be willing to make.

Response speed consistency throughout the Attention Network Task-Flanker Task (post ANT)Obtained from a test administered approximately 90 minutes after entering the classroom

Calculated as hit reaction time standard error for correct responses (HRT-SE). A higher HRT-SE indicates highly variable reactions related to inattentiveness

Combined risk taking scoreObtained from a test administered approximately 100 minutes after entering the classroom

Risk taking = 0.4729985 × "Risk preference score" + 0.5270015 × "Willingness to take risks", that follows the parameters of Falk et al (2018), where the "Risk preference score" is the final node in the risk tree (see the online appendix of Falk et al (2018)), which is a value between 1 and 32, ranked by the level of risk aversion, and the "Willingness to take risks" refers to the answer to the question on one's willingness to take risks.

Secondary Outcome Measures
NameTimeMethod
Impulsivity (from ANT)Obtained from a test administered approximately 90 minutes after entering the classroom

Number of incorrect responses (responses made in the opposite direction to the direction of the target arrow)

Self assessment of how good they are in mathObtained from a test administered approximately 100 minutes after entering the classroom

Answer to the question on how good they are in math.

Selective attention (from ANT)Obtained from a test administered approximately 90 minutes after entering the classroom

Number of omission errors (failure to respond)

Orienting score (from ANT)Obtained from a test administered approximately 90 minutes after entering the classroom

Subtracting the median RT for spatial cue from the RT for central cue (calculations performed after removing the incongruent trials)

Conflict score (executive attention) (from ANT)Obtained from a test administered approximately 90 minutes after entering the classroom

Participant's median RT for each flanker condition (across cue conditions) and subtracted the congruent from the incongruent RTs

Alerting score (from ANT)Obtained from a test administered approximately 90 minutes after entering the classroom

Subtracting the median RT for double cue from median RT for the no cue condition (calculations performed after removing the incongruent trials)

Trial Locations

Locations (1)

ISGlobal

🇪🇸

Barcelona, Spain

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