the Effects of Air Pollution on Respiratory Diseases in Children

• Conditions: Respiratory Disease

• Registration Number: NCT05483881
• Lead Sponsor: Beijing Children's Hospital

Brief Summary

The investigators expect to reveal the association between air pollution and childhood respiratory diseases through a multi-center observational study, and summarize the relationship between air pollution and childhood respiratory diseases.

Detailed Description

The investigators will collect the data of outpatient and emergency children in Beijing Children's hospital and other participating hospitals due to respiratory diseases from 2010 to 2021, , collect clinical data and basic information, obtain air pollution data and meteorological monitoring data and perform data processing and statistical analysis,，then analyzes the impact of air pollution on children's respiratory diseases.

Study Timeline

• Study First Submitted: 2022-01-14
• Study Start: 2022-05-15
• Status Verified: 2022-07
• Study First Submitted QC: 2022-07-29
• Last Update Submitted: 2022-07-29
• Study First Posted: 2022-08-02
• Last Update Posted: 2022-08-02
• Primary Completion: 2022-12-31
• Study Completion: 2022-12-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 2000000

Inclusion Criteria

• All children participating in this clinical study must meet all of the following criteria:

  1. Age: 0-18 years old, male and female
  2. Consultation for respiratory diseases
  3. Visit time is between 2010-2021
  4. Provide complete personally identifiable information and medical information

Exclusion Criteria

• All children with any of the following conditions must be excluded from this study:

  1. children who visit hospital don't for respiratory diseases
  2. children participating in this clinical study don't provide complete personally identifiable information and medical information
  3. Visit time is not between 2010-2021.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Major air pollutant concentrations	12 years	The air pollutant data comes from the daily air quality data published by the National Environmental Monitoring Center. Calculate the arithmetic average of the daily average concentrations of air pollutants (PM10, PM2.5, SO, NO, CO, etc.) Converted from air pollution index (API).

Secondary Outcome Measures

Name	Time	Method
Number of daily visits for respiratory diseases in outpatient and emergency departments	12 years	The number of daily outpatient visits for respiratory diseases( rhinitis, allergic rhinitis, upper respiratory tract infection, bronchitis and bronchiolitis, bronchiolitis obliterans, pneumonia, asthma , allergic cough, chronic cough, upper airway cough syndrome,etc.) in each hospital participating in this study during the study period.

Trial Locations

Locations (1)

Baoping Xu; 🇨🇳 Beijing, Beijing, China