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临床试验/NCT04709718
NCT04709718已完成不适用

Surgical Management of Giant Hepatic Hemangioma: a 10-year Single Center Experience

Université de Sousse0 个研究点目标入组 12 人开始时间: 2008年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
12
主要终点
number of patient getting good result after surgery

研究概览

简要总结

Hepatic hemangiomas are the commonest benign mesenchymal lesions of the liver. Most of these lesions are asymptomatic. Giant hepatic hemangiomas (GHH) (> 10 cm) are often symptomatic and require surgical intervention. This study aimed to describe the clinical findings, risk factors, diagnostic approach and management of GHH.

详细描述

Hepatic hemangiomas are the most common benign tumors of the liver with the incidence of 0.4 to 20% . They are most often discovered incidentally on imaging studies. Typical hemangiomas usually do not increase in size over time and therefore are unlikely to cause symptoms. Giant hepatic hemangiomas (GHH) are defined as hemangiomas larger than 5 cm . They are usually responsible for overt clinical symptoms and complications consisting, most often, of upper abdominal pain, hemorrhage, biliary compression, or a consumptive coagulopathy that may require prompt surgical intervention or other treatments . Management of liver hemangiomas ranges from close observation to surgery depending upon the site, size and symptoms .

It is widely accepted that intervention is indicated only for symptomatic hemangiomas. Surgical resection is indicated in patients with abdominal complaints or complications, or when diagnosis remains inconclusive. The ideal surgical treatment for GHH is still controversial. Enucleation is the preferred surgical method based on the existing literature. In this study, we report our 17-year experience of clinical management of GHH.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
15 Years 至 90 Years(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Radiological diagnosis of geant liver hamangioma.

排除标准

  • Radiological diagnosis of liver hemangioma less than 10cm.

结局指标

主要结局

number of patient getting good result after surgery

时间窗: 1 year

patient asymptomatic after surgery or not

次要结局

未报告次要终点

研究者

发起方
Université de Sousse
申办方类型
Other
责任方
Principal Investigator
主要研究者

ammar houssem

clinical professor

Université de Sousse

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