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临床试验/NCT07148648
NCT07148648已完成不适用

Institutional Experience With Chest Wall Reconstruction Using Sternal Steel Wires: A Case Series Study

University of Health Sciences Lahore1 个研究点 分布在 1 个国家目标入组 38 人开始时间: 2023年5月1日最近更新:

试验速览

阶段
不适用
状态
已完成
入组人数
38
试验地点
1
主要终点
Chest Wall Recoil

研究概览

简要总结

Chest wall resections, often performed for tumors, infections, or trauma, result in significant defects that require reconstruction to restore structural integrity and functionality. The use of twisted stainless steel wires (No. 05) for chest wall reconstruction offers a cost-effective and practical alternative. Steel wires provide robust structural support, allow dynamic movement of the chest wall during respiration, and are associated with improved postoperative pain control.

详细描述

The chest wall, a complex dynamic structure composed of both rigid and soft tissues, plays a vital role in protecting thoracic organs and maintaining the mechanics of respiration. Reconstruction following chest wall resection is critical not only to achieve defect closure but also to preserve respiratory mechanics and minimize postoperative complications. The primary goals include providing structural support, ensuring stability, and achieving soft tissue coverage while maintaining chest wall flexibility and minimizing pain. Chest wall reconstruction using sternal steel wires enable better chest wall recoil, which is crucial for maintaining normal respiratory mechanics. Additionally, studies suggest that the use of steel wires reduces the incidence of chronic pain, as they do not involve direct exposure to synthetic materials that could irritate surrounding tissues or provoke inflammatory responses. The affordability and simplicity of steel wire-based reconstruction make it particularly suitable for underserved populations in Pakistan, where healthcare resources are limited, and the majority of patients cannot afford expensive surgical materials.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients undergoing chest wall resection due to tumors or trauma.

排除标准

  • Patients with contraindications to General Anesthesia.
  • Patients having chest wall infection.
  • Patients with pre-existing chest wall deformities or severe chronic respiratory diseases.
  • Patients who undergo reoperation or develop intraoperative complications affecting the chest wall reconstruction.

结局指标

主要结局

Chest Wall Recoil

时间窗: 30 days post-operatively

Chest wall recoil after reconstruction is defined as maintenance of normal chest wall movement during respiration without paradoxical motion. It is assessed using spirometry (Forced Vital Capacity \[FVC\] and Forced Expiratory Volume in 1 second \[FEV1\]) compared with baseline/preoperative predicted values, radiological evaluation (postoperative chest X-rays for symmetrical expansion) and clinical observation (absence of paradoxical chest wall movement on examination). Preserving chest wall recoil is essential for normal breathing mechanics. Reconstruction with sternal steel wires aims to restore physiological elasticity, maintain ventilatory efficiency, and reduce respiratory complications.

次要结局

  • Post-Operative Pain Control(24 hours, 72 hours and 07 days)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Zeeshan Sarwar

Principal Investigator

University of Health Sciences Lahore

研究点 (1)

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