Plasma level of dabigatran comparison between geriatric and young patients with atrial fibrillatio
Phase 4
- Conditions
- Plasma level of dabigatran comparison between geriatric and young patients with atrial fibrillationdabigatran, geriatric, atrial fibrillation, plasma level, therapeutic drug monitoring
- Registration Number
- TCTR20230208005
- Lead Sponsor
- Faculty of Pharmacy, Silpakorn University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
1. Thai patient who was more than twenty years old and got dabigatran 150 milligrams or 110 milligrams twice daily for non-valvular atrial fibrillation indication.
2. Good compliance 100 percents and no change dabigatran at least 7 days.
3. The patient signed informed consent; if they can't decide, care given can sign informed consent.
Exclusion Criteria
1. Patient with mechanical valve replacement or moderate to severe mitral stenosis.
2. ESRD patient or creatinine clearance less than 30 ml/min.
3. Pregnancy or lactation patient.
4. Active bleeding
5. Platelet count less than 100,000 cell/mm3
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Dabigatran trough level 10-16 hours after the patient receives dabigatran Chromogenic assay,Dabigatran peak level 2-4 hours after the patient receives dabigatran Chromogenic assay
- Secondary Outcome Measures
Name Time Method /A N/A N/A