Changes in Brain Activity During Mirror Therapy and Virtual Reality Therapy

Not Applicable

• Conditions: Age of Probands 18 - 55 Years; Healthy

• Registration Number: NCT05219682
• Lead Sponsor: Charles University, Czech Republic

Brief Summary

The purpose of this study is to compare electroencephalographic activity in upper limb rehabilitation with mirror therapy and virtual reality rehabilitation.

Detailed Description

This is an experiment measuring EEG to healthy adult probands during mirror therapy and VR mirroring therapy in the upper limb. The experiment will be supplemented by haptic contact and stimulation of the upper limb with a foam roller. According to the instructions, the participants will perform a predetermined movement with one upper limb - clenching the fist. In one part with the mirror, in the other part the sensor for sensing the movement of the hand detects the movement, the software creates the illusion that the patient performs the same movement with the dominant and non-dominant upper limb. The patient sees on the screen the illusion of movement of both of his upper limbs. During therapy, the other upper limb will be tactively stimulated haptically and with a foam roller. Data collection will take place by measuring the electrical activity of the brain using an EEG device. The obtained data will then be processed and evaluated with the help of the sLORETA program. The aim of this work is to compare the brain activity from the above therapies with the resting state of the proband and to focus on the activity of mirror neurons.

Study Timeline

• Study Start: 2021-09-01
• Primary Completion: 2021-11-11
• Status Verified: 2022-01
• Study First Submitted: 2022-01-21
• Study First Submitted QC: 2022-01-21
• Last Update Submitted: 2022-01-21
• Study First Posted: 2022-02-02
• Last Update Posted: 2022-02-02
• Study Completion: 2022-04-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• a healthy individual with a valid medical examination.

Exclusion Criteria

• Having a stroke or other illness that is related to a disorder of movement of the upper limbs. Severe visual or auditory deficit and decompensated epilepsy due to screen movement tracking. Persons with acute (especially infectious) diseases did not participate in the research.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Comparison of EEG for each intervention versus the resting phase of the measurement	month	After processing the data in the sLORETA program, statistically significant places with different brain activity during interventions were identified, each type of intervention is evaluated separately.

Secondary Outcome Measures

Name	Time	Method
Comparison of electroencephalographic recordings from mirror therapy with therapy in virtual reality	month	After processing the data in the sLORETA program, statistically significant places with different brain activity during interventions were identified, each type of intervention is evaluated separately.

Trial Locations

Locations (1)

Faculty of Physical Education and Sport at Charles University; 🇨🇿 Prague, Czechia