ACTRN12616001649404撤回4 期
Correlation study of polymorphisms in genes SLC7A5 and SLC22A4 with the pregabalin efficacy and safety in patients with chronic low back pain.
Aristotle University of Thessaloniki, Greece0 个研究点目标入组 200 人开始时间: 2016年11月29日最近更新:
试验速览
- 阶段
- 4 期
- 状态
- 撤回
- 发起方
- 入组人数
- 200
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomised trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 79 Years（—）
- 性别
- All
入选标准
- •1.Age 18-79 years
- •2.Patients with lumbar radicular pain for more than three months
- •3.Patients with disc prolapse, spinal stenosis or failed surgery in the lumbar spine
- •4.Patients with neuropathic pain which is certified both by the discovery of nerve damage points as weakness, numbness, hyperalgesia, allodynia and with a NRS score larger that 4/10.
排除标准
- •1. Pain in the lumbar region stronger than the radicular pain
- •2. Significant motor deficits / disorders in urine bladder or bowel
- •3. Known depression with or without antidepressant treatment
- •4. Background of addiction or abuse
- •5. Current treatment with gabapentin, pregabalin or opioids
- •6. Diabetic or postherpetic neuropathy
- •7. Renal insufficiency, diabetes, congestive heart failure, thrombocytopenia.
- •8. Use of ACE inhibitors
研究者
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