CTRI/2025/03/082317尚未招募4 期
comparison of intrathecal hyperbaric bupivacaine 0.5% with morphine versus dexmedetomidine in infraumbilical surgeries
Afseen Fatima1 个研究点 分布在 1 个国家目标入组 180 人开始时间: 2025年3月15日最近更新:
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 180
- 试验地点
- 1
- 主要终点
- to compare the effects of intrathecal hyperbaric bupivacaine 0.5% with morphine versus dexmedetomidine by determining the duration of analgesia in infraumbilical surgeries
研究概览
简要总结
All patients posted for infraumbilical surgery will receive spinal anesthesia with 2.5 mg of hyperbaric bupivacaine (0.5%) added with either 100 micrograms of morphine or 5 micrograms of dexmedetomidine and compare the efficacy of both drugs to control post operative pain which would improve the outcome and early mobility and discharge.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant, Investigator and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •patient giving consent patient under ASA I and ASA II.
排除标准
- •1.Patients with pre-existing respiratory, cardiac, diabetes mellitus, neurological disorders, hepatic or renal disease
- •Patient having local infection at the site of Subarachnoid block (SAB)
- •Patient on anticoagulant therapy
- •Patient with raised Intracranial pressure (ICP)
- •Patients with spinal abnormalities
- •Those with contraindications for spinal anesthesia
- •Patient with known case of bradycardia, hypotension and drug allergy.
结局指标
主要结局
to compare the effects of intrathecal hyperbaric bupivacaine 0.5% with morphine versus dexmedetomidine by determining the duration of analgesia in infraumbilical surgeries
时间窗: 24 hrs
次要结局
- any adverse effects(24 hrs)
研究者
Afseen Fatima
GMC Haldwani
研究点 (1)
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