Comparative study of hyperbaric ropivacaine vs hyperbaric levobupivacaine for spinal anesthesia in Caesarean section : A prospective randomized double blind clinical study
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 116
- 试验地点
- 1
- 主要终点
- Pulse rate in both the groups will be compared
研究概览
简要总结
Generally, spinal anaesthesia is performed with hyperbaric racemic bupivacaine. Levobupivacaine and Ropivacaine are two new long acting local anesthetics ( pure S enantiomers of bupivacaine) that have been developed as an alternative to bupivacaine after evidence of its severe toxicity. In the present study, we would like to compare the hemodynamic stability and block characteristics of two pure S enantiomers of bupivacaine - hyperbaric Levobupivacaine (0.5%) and hyperbaric ropivacaine (0.75%) in patients undergoing elective Caesarean Section
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 40.00 Year(s)（—）
- 性别
- Female
入选标准
- •18-40 years
- •ASA physical status 2
- •Elective Caesarean Section
- •Singleton Full Term Pregnancy.
排除标准
- •Patient refusal
- •Patient on anti coagulant therapy
- •Patient with allergy to local anesthetics
- •Increased Intra cranial pressure
- •Severe hypovolemia
- •Height less than or equal to 150 centimetres
- •BMI greater than or equal to 30.
结局指标
主要结局
Pulse rate in both the groups will be compared
时间窗: before spinal anesthesia, immediately after spinal anestheia, every 5 minutes for the first half hour and every 15 minutes for the rest of the surgery
次要结局
- 1. Time required to reach sensory block up to T6(2. Time required to reach Maximum (peak) level of sensory block)
研究者
Sreenidhi Shukla
Government Medical College, Baroda