NCT07416084尚未招募2 期
Comparison of Maternal Hypotension After Spinal Anesthesia With Hyperbaric Bupivacaine Vs Isobaric Bupivacaine in Elective Cesarean Section With Colloid Preloading
干预措施
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Maternal hypotension
研究概览
简要总结
To assess the hemodynamic difference after spinal anesthesia with hyperbaric bupivacaine and isobaric bupivacaine in elective cesarean section
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •ASA II parturient with normal pregnancy Parturients undergoing elective cesarean section under spinal anesthesia Parturient refusing normal trial of labor, planned for ELLSCS under spinal anesthesia
排除标准
- •Patient refusal Parturient with known drug allergy to local anesthetics Parturients undergoing emergency cesarean section Spinal anesthesia converted to general anesthesia.
研究组 & 干预措施
Hyperbaric bupivacaine
Active Comparator
Hyperbaric bupivacaine used for spinal anesthesia
干预措施: Spinal anesthesia with hyperbaric bupivacaine (Drug)
Isobaric bupivacaine
Active Comparator
Isobaric bupivacaine used for spinal anesthesia
干预措施: Spinal anesthesia with isobaric bupivacaine (Drug)
结局指标
主要结局
Maternal hypotension
时间窗: Baseline
Incidence of maternal hypotension (MAP \< 60 mm Hg or drop in MAP \> 20% of the baseline) within 5 minutes after intrathecal drug administration
次要结局
- Nausea and vomiting(Baseline)
- APGAR score(Baseline)
- Conversion to general anesthesia(Baseline)
- Maternal MAP trend(Baseline)
- Maternal heart rate trend(Baseline)
- Use of vasopressors(Baseline)
研究者
Anum Fatima
Principal investigator
Liaquat National Hospital & Medical College
研究点 (1)
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