Comparison of hyperdry amniotic membrane transplantation and conjunctival autografting for primary pterygium
Not Applicable
Completed
- Conditions
- Eye DiseasesPrimary pterygiumPterygium
- Registration Number
- ISRCTN16900270
- Lead Sponsor
- The Second Hospital of Jilin University
- Brief Summary
2018 results in https://pubmed.ncbi.nlm.nih.gov/29764389/ (added 23/11/2020)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 130
Inclusion Criteria
1.The size of the pterygium is at least 2 mm onto the cornea or causing extreme irritation.
2. Most of the pterygium is translucent, and the episcleral vessels underneath the body of the pterygium can be identified
3. Patients 30-80 years old
Exclusion Criteria
1. Recurrent pterygium
2. Dry eye
3. Infection and inflammation of ocular area
4. Glaucoma
5. Previous ocular surgery in the study eye
6. Patients with a <6-month follow-up period
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Recurrence defined as the regrowth of the fibrovascular proliferation tissue invading the cornea again, checked at first week and then 1, 3, 6 and 12 months postoperatively
- Secondary Outcome Measures
Name Time Method <br> 1. Visual acuity is measured using a snellen chart at preoperative and postoperative day, first week and then 1, 3, 6, and 12 months postoperatively<br> 2. Intraocular pressure (IOP) measured using a non-contact tonometer at preoperative and postoperative day, first week and then 1, 3, 6, and 12 months postoperatively<br> 3. The size of the pterygium is measured using slit lamp at preoperative day<br> 4. Complications measured using slit lamp at first week and then 1, 3, 6, and 12 months postoperatively<br> 5. Pain is recorded at postoperative day, first week and then 1, 3, 6, and 12 months postoperatively<br> 6. Surgical times, recorded during the surgery<br>