Comparative study of the validity and reproducibility of real-time pH measurements in saliva and oral biofilm.
- Conditions
- HEALTHY VOLUNTEERS
- Registration Number
- DRKS00030617
- Lead Sponsor
- niversitätsklinikum Schleswig-Holstein, Campus KielKlinik für Zahnerhaltungskunde und Parodontologie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 10
Generally healthy persons to whom the exclusion criteria do not apply.
Exclusion criteria for participation in the study are a BMI <18.5 or >29.5 kg/m², metabolic or endocrine diseases, malabsorption syndrome, allergies, smoking, alcohol and drug abuse, medication (such as e.g. antidepressants, antibiotics), presence of a defibrillator or pacemaker, nickel allergy, known allergies to the materials used, MRI examination scheduled during the study period, reflux disease, bulimia, medical conditions (such as HIV, hepatitis, or diabetes), and epilepsy.
Further dental exclusion criteria are existing tooth structure defects requiring treatment, a periodontal screening index (PSI) >2, professional dental cleaning less than 4 weeks ago, no stable occlusion, orthodontic treatment performed at the time of the study, wearing of an occlusal splint (''grinding splint''), and no sufficient number of teeth present, i.e., no terminal molar in the fourth or third quadrant and more than 2 missing teeth per quadrant.
Also excluded are dental students or employees in a dependent relationship.
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method pH measurement in saliva and biofilm over four days
- Secondary Outcome Measures
Name Time Method Saliva flow rate, saliva buffer capacity, plaque volume (API), biofilm sample