Somatic Symptoms in Autism Spectrum Disorder: Data Integration

Completed

• Conditions: Somatic Symptom Disorder; Autism Spectrum Disorder
• Interventions: Other: No intervention involved

• Registration Number: NCT05886361
• Lead Sponsor: National Taiwan University Hospital

Brief Summary

Autistic patients have higher chances commorbid somatic symptoms. Therefore, it leads to more health-related concerns, such as autoimmune disease, gastrointestinal disease, cardiovascular disease, autonomic disorders. On average, autistic patient's life span is 16 years shorter than non-autistic patients. Furthermore, autistic patients are not able to convey or communicate their somatic symptoms in a clear and comprehensive manner. This leads to unable to receive proper health care in a timely manner.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-01-01
• Primary Completion: 2022-05-31
• Study Completion: 2022-05-31
• Status Verified: 2022-06
• Study First Submitted: 2023-05-04
• Study First Submitted QC: 2023-05-23
• Last Update Submitted: 2023-05-23
• Study First Posted: 2023-06-02
• Last Update Posted: 2023-06-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1423

Inclusion Criteria

• ASD group: diagnosed with DSM-5 autism spectrum disorder
• clinical group: anxiety, depression, somatic disorder who are non-psychotic and non-organic
• control group: healthy control without psychiatric disorder or chronic somatic symptoms
• age between 15 and 70

Exclusion Criteria

• psychiatric disorders such as schezophrenia, mood disorder.
• major physical disorder which can be potentially lethal
• who cannot read or comprehend the survey and questionnaire

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Control	No intervention involved	Healthy control without psychiatric disorder or chronic somatic symptoms
ASD	No intervention involved	Diagnosed with DSM-5 autism spectrum disorder
Clinical	No intervention involved	Patients with anxiety, depression, somatic symptoms which are non-psychotic and non-organic

Primary Outcome Measures

Name	Time	Method
Patient health questionnaire-15, PHQ-15	8 years	range from 0 to 2 for each item, total score range from 0 to 30. Higher the score, worse the level of somatization
Health assessment questionnairse, HAQ	8 years	range from 0 to 3 for each item. Higher the score, worse the disability
Beck depression inventory, BDI	8 years	range from 0 to 3 for each item. Higher the score, worse the depression
Beck anxiety inventory	8 years	range from 0 to 3 for each item. Total score 0 to 63. Higher the score, worse the anxiety