Effect of Sub-Tenon's versus peribulbar anesthesia on postoperative nausea and vomiting in muscle traction ophthalmic surgeries in adults. A comparative randomized control study

Phase 3

Recruiting

• Conditions: Anaesthesia

• Registration Number: PACTR202206633862234
• Lead Sponsor: Cairo university faculty if medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-06-15
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 42

Inclusion Criteria

Patients aged 18 to 65 years, of both sexes.

ASA I, II.

patients undergoing muscle traction eye surgeries (buckling).

Exclusion Criteria

Patient refusal.
Uncooperative patient.
Impaired mental status, communication difficulty as deafness or language barrier.
ASA III-IV
Patients <18 years, >65 years
Axial eye length >28 mm.
Clotting and coagulation abnormalities.
ophthalmitis or inflammatory eye pathology
raised IOP
eye injury
single eye
allergy to amide type local anaesthetic
patients known to have reduced plasma cholinesterase concentrations (reduced articaine metabolism)
Patient had received an antiemetic drug or a drug with antiemetic properties during the 24 h before anaesthesia.
Patient had a body mass index =36.
Pregnant or breastfeeding women.
patient had a condition requiring chronic opioid use
patient had history of GIT pathology (gastritis, hematemesis, peptic ulcer).
Patients on corticosteroids therapy.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The percent of patients who experienced nausea and vomiting over the first 24 hrs postoperative in the Sub-tenon’s block group compared with Peribulbar block group and general anesthesia group

Secondary Outcome Measures

Name	Time	Method
Compare postoperative analgesia using VRS ;Compare Intraoperative analgesia in each group; by measuring systolic, diastolic and mean BP, HR at induction (T0), immediately after induction (T1), at incision (T2), and every 15 min till the end of the procedure and serum cortisol and glucose level (baseline and 30 mins after surgery and at end of surgery).<br>