Effect of the timing of antibiotic prophylaxis before gastrointestinal and vascular surgery with laparotomy on the incidence of incisional hernias

Conditions: Incisional hernia without obstruction or gangrene
Incisional hernia with obstruction, without gangrene
K43.0
K43.1
K43.2
Incisional hernia with gangrene

Registration Number: DRKS00031551

Lead Sponsor: niversitätsklinikum Halle (Saale)

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 415

Inclusion Criteria

• Gastrointestinal or vascular surgery with laparotomy (midline incision, transverse incision, subcostal incision, Pfannenstiel incision)
• Surgery in the period from 1 January 2018 to 31 December 2020
• Surgery was planned

Exclusion Criteria

• Absent ability to provide informed consent
• A utilitiy incision to remove the resection specimen during a laparoscopic procedure is not considered a laparotomy
• Re-laparotomy within 30 days after primary surgery
• Conversion to laparotomy during laparoscopic surgery

Study & Design

Study Type: observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Time to the occurrence of incisional hernia after primary surgery

Secondary Outcome Measures

Name	Time	Method
• Incidence of incisional hernia throughout the postoperative period up to the time of data collection <br>• Therapeutic relevance of a developed incisional hernia (none, symptomatic treatment, surgery)<br>• Frequency of hospital readmissions due to complications caused by incisional hernia <br>• Occurrence of a postoperative fascial dehiscence<br>• Frequency and severity of postoperative complications (according to the Clavien-Dindo-Classification) <br>• Frequency and severity of SSI (Surgical Site Infection, severity according to<br>CDC-Classification) <br>• Frequency, timing and reason for a re-laparotomy after primary surgery