Adherence of Stalevo, Entacapone and Levodopa

Completed

• Conditions: Parkinson's Disease

• Registration Number: NCT00245700
• Lead Sponsor: South Glasgow University Hospitals NHS Trust

Brief Summary

To test if combining two antiparkinson drugs into a single tablet improves accuracy of medicine intake by the patient.

To test if patients with Parkinson's disease who take medicines at regular time intervals have smoother symptom control.

Detailed Description

Not available

Study Timeline

• Study Start: 2005-04
• Study First Submitted: 2005-10-27
• Study First Submitted QC: 2005-10-27
• Study First Posted: 2005-10-28
• Study Completion: 2006-07
• Status Verified: 2008-05
• Last Update Submitted: 2008-05-22
• Last Update Posted: 2008-05-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 14

Inclusion Criteria

• Patients diagnosed with Parkinson's disease aged between 18 and 85 years fulfilling UK Brain Bank criteria.
• Current levodopa therapy prescribed on a regular basis three or more times per day but requiring entacapone because of 'wearing off'
• Able to manipulate electronic monitoring bottles and complete questionnaires

Exclusion Criteria

• Current use of compliance aid such that study participation would be detrimental to patient's adherence
• Pregnancy or breast feeding
• Excess alcohol (over 21 units per week for women and 28 units for men)
• Mini mental state examination of less than 26.
• Severe depression (Geriatric depression score over 20)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Southern General Hospital; 🇬🇧 Glasgow, Scotland, United Kingdom