Phototherapeutic Keratectomy With Mitomycin C in Adenoviral Infiltrates
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Refractive data, visual acuity, slit lamp findings, subjective evaluation, topography patterns, pachymetry measurements.
研究概览
简要总结
The present study was designed to evaluate the treatment of adenoviral corneal opacities with PTK and mitomycin C.
详细描述
Epidemic keratoconjunctivitis is a very common disease, some patients developed a complication after the infection wich is corneal infiltration. Topical treatment sometimes helps to avoid loss of visual acuity. Therefore recurrence of the opacities after topical drops is observed. When corneal fibrosis occur is difficult to achieve visual rehabilitation with topical approach. This study evaluate pre and postoperative data of patients with subepithelial fibrosis caused by adenoviral infiltrates submitted to phototherapeutic keratectomy (PTK) using mitomycin C.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •visual acuity worse than 20/40, caused by central subepithelial fibrosis
排除标准
- •pregnancy, age less than 18 years-old or more than 80 years-old.
- •diabetes, autoimmune diseases, corneal thickness less tha 400 micron.
结局指标
主要结局
Refractive data, visual acuity, slit lamp findings, subjective evaluation, topography patterns, pachymetry measurements.
时间窗: one year
次要结局
- wavefront analysis, anterior segment tomography data, corneal biomechanics data.(one year)