Dexamethasone for the prevention of a pain flare after palliative radiotherapy for painful bone metastases: a multicenter double-blind placebo-controlled randomized study - Dexamethasone for pain flare after radiotherapy
- Conditions
- Bone metastases
- Registration Number
- EUCTR2010-020174-42-NL
- Lead Sponsor
- ZonMw
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Authorised-recruitment may be ongoing or finished
- Sex
- All
- Target Recruitment
- Not specified
Uncomplicated painful bone metastases
Indication for single or short course of radiotherapy
Age >17 years
Solid tumor
Pain intensity on a numeric rating scale 2-8
No immediately expected changes in analgesic medication
Ability to complete Dutch questionnaire
informed consent
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range
Hematological malignancy
Multiple sites to be irradiated
Patinets who have been treated before with palliative radiotherapy for painful bone metastases
Current use of corticosteroids
Long-ternm schedule radiotherapy (>6 fractions)
Life expectancy ,8 weeks
Karnofsky Performance Statsu 40 or less
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method