Cardiac 4D MR Velocity Mapping in Repaired Tetralogy of Fallot Patients: Evaluation of Pulmonary Regurgitant Fraction and Ventricular Volume
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Magnetic Resonance Imaging
- Sponsor
- Centre Hospitalier Universitaire, Amiens
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Regurgitant fraction comparison
- Last Updated
- 7 years ago
Overview
Brief Summary
MRI with 4D flow permits to assess the hemodynamic parameters in a parent vessel and its branches inside the same sequence.
Detailed Description
MRI with 4D flow permits to assess the hemodynamic parameters in a parent vessel and its branches inside the same sequence. The objective of the project is to compare the regurgitant fraction in the pulmonary artery (PA) measured using 4D MR-flow and standard 2D MR-flow in repaired Tetralogy of Fallot (rTOF) patients. The consistency of the 4D flow quantization will be assessed assuming mass conservation in the pulmonary artery tree (PA flow =LeftPA flow +RightPA flow ? ).
Investigators
Eligibility Criteria
Inclusion Criteria
- •Tetralogy of Fallot patients
- •referred for clinical MRI examination
- •≥ 15 years
Exclusion Criteria
- •Anyone with a classic contraindication to MRI
- •Severe obesity
- •Gadolinium chelate allergy
- •\< 15 years
- •counter-indication to MRI examination
- •vulnerable person
Outcomes
Primary Outcomes
Regurgitant fraction comparison
Time Frame: Day 0
The primary objective of the project is to compare the regurgitant fraction in the pulmonary artery (PA) measured with 4D MR-flow and standard 2D MR-flow.
Secondary Outcomes
- Pulmonary arteries flows(Day 0)
- Right ventricular volume(Day 0)