Treatment of essential hand tremor: Dysport versus propranolol
Phase 3
- Conditions
- essential hand tremor.Essential tremor
- Registration Number
- IRCT201607022415N2
- Lead Sponsor
- Vice chancellor for research, army university of medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 78
Inclusion Criteria
essential hand tremor with severity equal or greater than 2 according to tremor research group essential tremor rating assessment scale (TETRAS) version 3.1 (paragraph 4); normal thyroid function test; age higher than 18 years;
exclusion criteria: drug induced tremor; pregnancy and lactation; allergy to cow milk protein; propranolol contraindications for example heart block, congestive heart failure, diabetes melitus, asthma and etc; history of botulinum injection in upper limb; recent botulinum injection in any part of body since 8 months ago; allergy to botulinum; history of myasthenia gravis or suspicious to myasthenia gravis; parkinson disease; use of anti-dopaminergic medications
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hand tremor severity. Timepoint: before treatment, one and two and three months following the start of treatment. Method of measurement: tremor research group essential tremor rating assessment scale (TETRAS).;Quality of life. Timepoint: before treatment, two months following start of treatment. Method of measurement: short form 36 (SF-36) quality of life questionnaire.
- Secondary Outcome Measures
Name Time Method Side effects. Timepoint: one and two and three months following start of treatment. Method of measurement: history taking.