Analgesic Efficacy Of Ultrasound Guided Erector Spinae Block Versus Intrathecal Morphine In Patients Undergoing Percutaneous Nephrolithotomy Surgery: A Prospective Randomised Comparative Pilot Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Perioperative opioid consumption in Erector spinae block and Intrathecal Morphine Groups
研究概览
简要总结
Many modalities like Intravenous opioids, local anaesthetic infiltration, intrathecal nerve blocks, regional nerve blocks like paravertebral and intercostal blocks have been used traditionally to control pain after PCNL surgery. However the efficacy of these blocks has not been proved. The erector spinae block is a relatively newer technique that reportedly provides effective analgesia after abdominal surgery. We hypothesise that erector spinae blockade will provide adequate analgesia with less side effects compare to intrathecal morphine in patients undergoing Percutaneous Nephrolithotomy surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA 1 & 2 patients scheduled to undergo elective percutaneous nephrolithotomy surgery for renal and upper ureteric stone requiring bladder catheterization under general anesthesia.
排除标准
- •1.Patients refusal 2.ASA III OR IV 3.Allergy to any of the study drugs 4.Contraindications to regional technique e.g., allergy to local anaesthetic drugs, infection around site of block ,any coagulation disorder, sepsis
- •History of analgesic dependence (long term use) and opiate tolerance
- •Contraindications to intrathecal morphine e.g., local infection (administration site), systemic infection, coagulopathy, raised intracranial pressure, metastatic disease of the vertebral column, sleep apnoea syndrome, or a history of postdural puncture headache (PDPH) or frequent headaches of any type.
- •Epilepsy and psychiatric disturbances.
结局指标
主要结局
Perioperative opioid consumption in Erector spinae block and Intrathecal Morphine Groups
时间窗: Intraoperatively fentanyl usefrom the beginning of the surgery till the end of surgery. | Postoperative fentanyl usage at 0 min, 30 mins,1 hr, 2 hrs, 4 hrs, 6 hrs and 24 hrs
次要结局
- 1. Hemodynamic response to surgical stimulus during the procedure(2. Postoperative nausea and vomiting till 24 hours)