Comparison of the Effects of Aerobic Exercise and Computerized Cognitive Stimulation in Patients With Schizophrenia - A Randomized Controlled Trial

Not Applicable

Completed

• Conditions: Exercise; Computerized Cognitive Stimulation; Schizophrenia

• Registration Number: NCT06572657
• Lead Sponsor: Dr. Lutfi Kirdar Kartal Training and Research Hospital

Brief Summary

Schizophrenia is a chronic mental disorder characterized by the occurrence of both positive symptoms, such as hallucinations and delusions, and negative symptoms, such as apathy and withdrawal, repetition of cognitive skills and disorganization. There are approximately 20 million people with schizophrenia worldwide and this number will continue to increase every year.

Detailed Description

The aim of this study was to compare the effects of computer-based cognitive stimulation and aerobic/strengthening exercises on symptom severity, cognition and depression in schizophrenia patients receiving community mental health center services.

Study Timeline

• Study Start: 2024-02-02
• Status Verified: 2024-08
• Study First Submitted: 2024-08-23
• Study First Submitted QC: 2024-08-23
• Primary Completion: 2024-08-26
• Study First Posted: 2024-08-27
• Study Completion: 2024-09-06
• Last Update Submitted: 2025-09-15
• Last Update Posted: 2025-09-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 58

Inclusion Criteria

• Individuals diagnosed with schizophrenia by a physician according to DSM-V criteria Patients treated at TRSM Individuals diagnosed with schizophrenia between the ages of 20-60

Exclusion Criteria

• Those who did not give consent to participate in the study Patients with a diagnosis other than schizophrenia Pregnancy Patients with chronic metabolic diseases such as diabetes, heart problems and cancer

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Montreal Cognitive Assessment Scale	12 weeks	MOCA is a short cognitive assessment method developed to detect particularly mild stages of cognitive impairment.
Frontal Assessment Battery	12 weeks	Frontal Assessment Battery consists of six subtests for assessing executive functions; the scale is scored from 0 to 18, with higher scores indicating better frontal functions.

Trial Locations

Locations (1)

Kartal Dr Lütfi Kırdar Şehir Hastanesi; Istanbul, Turkey (Türkiye)