Investigating the effect of curcumin in rheumatoid arthritis

Phase 3

Recruiting

• Conditions: Rheumatoid Arthritis.; Rheumatoid arthritis, unspecified; M06.9

• Registration Number: IRCT20101014004934N3
• Lead Sponsor: Kashan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 January 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Patients with rheumatoid arthritis based on diagnostic criteria
Age 20-70 years
No smoking

Exclusion Criteria

Reluctance to cooperate
Hypothyroidism or hyperthyroidism
Consumption of any type of supplement (vitamins, salts, etc.) by the patient during the last 3 months
Having any acute and active infection

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Severity of clinical symptoms before and after treatment. Timepoint: Before the start of the intervention and twelve weeks later. Method of measurement: Based on Disease Activity Score 28 (DAS28) and Visual Analog Scale (VAS).;Total plasma antioxidant. Timepoint: Before the start of the intervention and twelve weeks later. Method of measurement: Antioxidant capacity of plasma is determined by ELISA method.;Plasma malondialdehyde. Timepoint: Before the start of the intervention and twelve weeks later. Method of measurement: Determination of malondialdehyde is done by ELISA method.;Serum Hs-CRP. Timepoint: Before the start of the intervention and twelve weeks later. Method of measurement: Serum hs-CRP is performed using an ELISA device (immunoassay method).