Effectiveness of a physician-centered educational intervention to improve hypertension management for patients with resistant hypertension: a cluster randomized trial in primary care

Not Applicable

Conditions: resistant hypertension
I10-I15
Hypertensive diseases

Registration Number: DRKS00008781

Lead Sponsor: Institut für Allgemeinmedizin, Universitätsklinikum Essen, Universität Duisburg-Essen

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: All

Target Recruitment: 1224

Inclusion Criteria

resistant hypertension, defined as blood pressure =130/80 mmHg on ambulatory blood pressure monitoring (24 hours) despite therapy with =3 antihypertensive agents

Exclusion Criteria

Patients not able to provide informed consent, patients with white coat hypertension (office blood pressure uncontrolled, but controlled in ambulatory blood pressure monitoring), pregnancy-related hypertension, patients undergoing dialysis for renal failure

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Treatment success: Rate of patients with normalized blood pressure in a 24-hour ambulatory blood pressure monitoring (<130/80 mmHg) and/or a blood pressure reduction of =20 mmHg systolic and/or =10 mmHg diastolic (measured by ambulatory blood pressure monitoring before the intervention and 12 months later)

Secondary Outcome Measures

Name	Time	Method
a) Changes in mean systolic ambulatory blood pressure (24 hours, daytime, nighttime), b) Changes in mean diastolic ambulatory blood pressure (24 hours, daytime, nighttime), c) Changes of non-pharmacological and pharmacological treatment, d) Rate of cardiovascular events or death from any cause, e) Increase of physicians’ knowledge: diagnostic and therapeutic strategies for resistant hypertension, f) Number and kind of practice tools implemented