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A Phase I Clinical Trial to Investigate the Safety, Tolerability and Pharmacokinetic Characteristics of LC28-0126.

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: Placebo
Registration Number
NCT03196804
Lead Sponsor
LG Chem
Brief Summary

To assess the safety, tolerability and pharmacokinetic characteristics of LC-28-0126 multiple iv injection in healthy male subjects.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Male
Target Recruitment
32
Inclusion Criteria
  • Healthy male subjects between the ages of 19 and 45 years at screening.
  • Subjects with BMI between 18.0(inclusive) and 27.0 kg/m2 (exclusive); and a total body weight between 55 kg (inclusive) and 90 kg (exclusive)
Exclusion Criteria
  • Participation in a clinical research study within the previous 3 months
  • Regular alcohol consumption >21 units per week.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
PlaceboPlaceboPlacebo of LC28-0126
LC28-0126LC28-0126LC28-0126(IV)
Primary Outcome Measures
NameTimeMethod
Adverse events18 days
Secondary Outcome Measures
NameTimeMethod
Cmaxup to 6 days post-dose
AUCup to 6 days post-dose

Trial Locations

Locations (1)

Seoul National University Hospital, Clinical Trial Center

🇰🇷

Seoul, Korea, Republic of

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