IIH Provoke: headache mechanisms in idiopathic intracranial hypertensio

Not Applicable

• Conditions: Idiopathic intracranial hypertension; Nervous System Diseases

• Registration Number: ISRCTN13251508
• Lead Sponsor: niversity of Birmingham

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-10-24
• Last Update Posted: 11 March 2024
• Study Completion: 2025-07-31

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

1. Aged between 18 and 60 years old
2. Previous diagnosis of idiopathic intracranial hypertension (IIH)
3. Able to give informed consent

Exclusion Criteria

1. Aged less than 18 or older than 60 years old
2. Optic nerve elevation exclusively due to pseudopapilloedema
3. Previous migraine history prior to the diagnosis of IIH (or non-IIH headache) > 1 day per month
4. Pregnant or trying to conceive
5. Significant co-morbidity; such that in the opinion of the investigator it would not be in the
participant’s best interest to participate in the trial
6. Known cardiovascular or cerebrovascular disease
7. Medication overuse
8. Inability to comply with study schedule or follow-up
9. Currently using Glucagon-like peptide-1 receptor (GLP-1R) agonist or Dipeptidyl-peptidase 4
(DPP-4) inhibitor
10. Contra-indications to undergoing a surgical procedure

Study & Design

• Study Type: Interventional
• Study Design: Not specified