Comparative study of two ayurvedic formulation in gout

Phase 2

Not yet recruiting

• Conditions: Hyperuricemia without signs of inflammatory arthritis and tophaceous disease. Ayurveda Condition: GOUT(PRIMARY HYPERURICEMIA),

• Registration Number: CTRI/2021/08/035594
• Lead Sponsor: Patanjali Ayurvedic College

Brief Summary

Group-A - 2-2 tablet each of Kaishore guggulu and Giloy ghan vati will be given to the

patients.



Group-B - 40 ml of Bodhivriksha kashaya with 2 tsf madhu will be

given to the patients.



Kaishor guggulu and Giloy ghan vati will be advice to take 1 st dose in morning at 9:00 a.m.

and 2 nd dose at 9:00 p.m. after having breakfast.



Bodhivriksha kashaya with madhu will be advice to take 1 st dose in the morning at 6:00 a.m.

and 2 nd dose at 6:00 p.m. on empty stomach.



Route of administration- oral

Follow up : The follow up will be done after 15 days and 1 month during the trial of

1 month to observe the effects of treatment or any adverse effects on the patients.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2021-04-08
• Study Start: 2021-08-18

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

• 1.Patients between the age group of 18 -70 years will be selected.
• 2.Patients having serum uric acid > 7mg/dl in male and> 6mg/dl in female or more than upper normal limit.
• 3.Patients not having any associated chronic ailment.
• 4.Patient with symptoms of Vatarakta and primary hyperuricaemia will be selected for the study.
• 5.Patients irrespective of sex, religion, occupation will be selected for the study.

Exclusion Criteria

• 1.Patients aged < 18 years or> 70 years will be excluded.
• 2.Pregnant or lactating mother will be excluded.
• 3.Patients with renal disorder, liver disease, osteoarthritis, rheumatoid arthritis, Diabetes mellitus, obesity, hypothyroidism or hyperthyroidism, chronic haemolytic anaemia, auto immune disorders, and any other co-morbid condition will be excluded.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.Itching	Before intervention with Kaishore guggulu, giloyghan vati and Bodhivriksha Kashaya
3.Burning sensation	Before intervention with Kaishore guggulu, giloyghan vati and Bodhivriksha Kashaya
4.Malaise	Before intervention with Kaishore guggulu, giloyghan vati and Bodhivriksha Kashaya
1.Sign of primary hyperuricemia	Before intervention with Kaishore guggulu, giloyghan vati and Bodhivriksha Kashaya
Tenderness	Before intervention with Kaishore guggulu, giloyghan vati and Bodhivriksha Kashaya
Subjective Parameters-	Before intervention with Kaishore guggulu, giloyghan vati and Bodhivriksha Kashaya
2.Pain	Before intervention with Kaishore guggulu, giloyghan vati and Bodhivriksha Kashaya
2.Serum uric acid before the treatment	Before intervention with Kaishore guggulu, giloyghan vati and Bodhivriksha Kashaya
Objective Parameters-	Before intervention with Kaishore guggulu, giloyghan vati and Bodhivriksha Kashaya
Local colour changes in the skin	Before intervention with Kaishore guggulu, giloyghan vati and Bodhivriksha Kashaya

Secondary Outcome Measures

Name	Time	Method
Subjective Parameters-	1.Itching

Trial Locations

Locations (1)

Patanjali Ayurved Hospital; 🇮🇳 Hardwar, UTTARANCHAL, India

Patanjali Ayurved Hospital

🇮🇳Hardwar, UTTARANCHAL, India

Dr Rajani Agrahari

Principal investigator

7088506942

rajniagarhari@gmail.com