Inherited Alzheimer Network
- Conditions
- Alzheimer diseaseTherapeutic area: Diseases [C] - Nervous System Diseases [C10]
- Registration Number
- EUCTR2018-002319-86-ES
- Lead Sponsor
- Fundació Clínic per a la Recerca Biomèdica
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Authorised-recruitment may be ongoing or finished
- Sex
- Not specified
- Target Recruitment
- 45
1. Signature of informed consent by the participant and companion of the study before carrying out any procedure related to the study
2. Age = 18 years and the child of an individual affected (clinically or by tests) of genetic Alzheimer's disease in a pedigree with a known mutation causing genetic Alzheimer's disease.
3. Cognitively normal (Clinical dementia Rating scale, CDR = 0) or with cognitive impairment in mild phase (CDR 0.5 or 1).
4. The participant has identified two people who are not their blood siblings who can serve as companions to the study.
5. Sufficient knowledge of the Castilian language (equivalent to 6th grade of primary school).
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 30
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 15
1. The participant has a medical or psychiatric illness that would interfere according to clinical criteria in the initial evaluation and / or follow-up evaluations.
2. The participant has an advanced cognitive impairment that requires admission to a long-term care center.
3. The recruitment of a subject with cognitive impairment must be pre-approved by the Coordinating Group of DIAN.
4. Women who are pregnant or breast-feeding or who have planned to become pregnant during the study period
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method