Contraceptive Use and Respiratory Conditions Among Scottish Women

Completed

• Conditions: Asthma

• Registration Number: NCT02039102
• Lead Sponsor: University of Edinburgh

Brief Summary

Studies examining the sex differences in the epidemiology and morbidity patterns of asthma show that the rates of disease severity, healthcare utilisation, and poor quality of life are considerably higher in women than in men, and this has been attributed to endogenous and exogenous sex hormonal factors. Studies examining the impact of use of hormonal contraceptives on the risk of asthma and asthma-related conditions are few, yet findings are conflicting.

In the present study, the investigators utilize data from the Scottish Health Survey, a national representative sample, to investigate the associations between current use of hormonal contraceptives and the prevalence of self-reported doctor-diagnosed current asthma and wheezing symptoms in Scottish women. The investigators hypothesize that while current use of any hormonal contraceptives and combined oral pills are associated with higher prevalence of asthma and asthma outcomes, current use of progesterone-only contraceptives is not associated with asthma. A secondary aim of the current study is to examine whether there is evidence of any biological interaction between use of hormonal contraceptives and BMI in relation to the risk of asthma and asthma outcomes.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-12
• Study First Submitted: 2014-01-15
• Study First Submitted QC: 2014-01-16
• Study First Posted: 2014-01-17
• Primary Completion: 2018-09
• Study Completion: 2018-09
• Status Verified: 2021-06
• Last Update Submitted: 2021-06-18
• Last Update Posted: 2021-06-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 3257

Inclusion Criteria

• Non-pregnant
• Woman
• 16-45 years old

Exclusion Criteria

• Pregnant
• Man
• Younger than 16 years or older than 45 years old

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Self-reported doctor-diagnosed current asthma	During the past 12 months

Secondary Outcome Measures

Name	Time	Method
Self-reported wheezing symptom	During the past 12 months
Self-reported current treatment for asthma/wheeze	During the past 12 months

Trial Locations

Locations (1)

University of Ediburgh; 🇬🇧 Edinburgh, United Kingdom