Effect of vitamin-D supplementation on the progression to overt diabetes of prediabetes with vitamin-D deficiency: A randomized controlled trial.

Research Society for Study of Diabetes in India West Bengal Chapter0 个研究点目标入组 100 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•Patients and their family members attending diabetic clinic, endocrine out patient department (OPD) services and health camps conducted by the department of Endocrinology & Metabolism, across the city of Kolkata, will be considered. Patients >30 years and <80 years of age will be considered. Family members of diabetic patients who gave consent would be screened by 75 gm OGTT with blood glucose measured at fasting, 1 hour and 2 hours post glucose.. Patients attending OPD with reports of impaired fasting glucose (IFG; 100-125mg/dl) and/or impaired glucose tolerance (IGT; 140-199mg/dl) would also undergo the same 75 gm OGTT and blood sugars would be measured at fasting, 1hour post glucose (1hPG) and 2hours post glucose (2hPG). Patients with fasting blood sugar between 100-125 mg/dl or 2 hour post meal blood sugar between 140-199mg/dl documented by 2 separate measurements over a week period would only be considered for the study.

•Patients with history of diabetes or any history of oral hypoglycemic agents, insulin use would not be considered. Also patients with associated disorders like primary hyperparathyroidism, chronic kidney disease, liver disease, any chronic illness, malignancy, chronic drug use like anti-epileptic agents, oral contraceptive pills, steroids which are likely to interfere with vitamin-D metabolism will be excluded. Patients with pregnancy would be excluded. Treated patients of hypothyroidism who are clinically and biochemically euthyroid will be considered for the study. Patients with history of calcium or vitamin-D supplementation would also be excluded.

发起方

Research Society for Study of Diabetes in India West Bengal Chapter