Caffeine, Resistance Exercise and Muscle/Cerebral Oxygenation

Not Applicable

Completed

• Conditions: Caffeine and Resistance Exercise

• Registration Number: NCT07001176
• Lead Sponsor: University of Alcala

Brief Summary

Introduction: Several studies have evaluated and confirmed the ergogenic effects of acute caffeine intake on sports performance. However, the mechanism responsible for this ergogenic effect remains to be elucidated.

Objectives: This study aims to evaluate the acute effects of caffeine intake on muscle and cerebral oxygen during muscular strength, power, muscle endurance performance. and muscle electrical activity in young adults.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-01-01
• Primary Completion: 2024-12-23
• Study Completion: 2024-12-23
• Status Verified: 2025-05
• Study First Submitted: 2025-05-23
• Study First Submitted QC: 2025-05-23
• Last Update Submitted: 2025-05-23
• Study First Posted: 2025-06-03
• Last Update Posted: 2025-06-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 12

Inclusion Criteria

• Age between 18 and 35 years.
• Body Mass Index (BMI) < 25 kg/m².
• Resistance-trained individuals (more than 2 years of structured training).
• Healthy men and women without neurological, cardiometabolic, immunological, or physical conditions that prevent them from exercising.
• Participants must be able to perform the tests described in the following section.

Exclusion Criteria

• History of neuromuscular diseases, heart disease, or conditions that may affect liver or muscle metabolism.
• Use of drugs, stimulants, or sports supplements that could interfere with the dietary supplement used in the study.
• Sedentary habits (less than 150 minutes/week of moderate exercise).
• Having undergone prolonged periods of physical inactivity in the 6 months prior to the study.
• Engaging in strenuous exercise within 48 hours prior to the tests.
• Failure to replicate the same food intake on both experimental days.
• Consumption of caffeine or any other stimulant after 6 pm on the day before the tests, to avoid headaches, discomfort, or lethargy in regular caffeine consumers.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Muscle Oxygenation	Through study completion, an average of 2 weeks	Measuring oxygen in the muscle before and after exercise.
Cerebral oxygenation	Through study completion, an average of 2 weeks	Measuring cerebral oxygenation before and after exercise.
Number of repetitions performed in 1 set at 65%1RM until task failure	Through study completion, an average of 2 weeks
Bar velocity deplacement performed in 1 set at 65%1RM until task failure	Through study completion, an average of 2 weeks	In bench press and back squat exercises
Power output generated in 1 set at 65%1RM until task failure	Through study completion, an average of 2 weeks	In bench press and back squat exercise

Trial Locations

Locations (1)

Facultad de Medicina y Ciencias de la Salud. Universidad de Alcalá; 🇪🇸 Alcalá de Henares, Madrid, Spain