Effects of pennyroyal in treatment of functional dyspepsia
- Conditions
- Dyspepsia.Dyspepsia
- Registration Number
- IRCT201602172288N9
- Lead Sponsor
- Vice Chancellor for research of ACECR Institute of Medicinal Plants
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 100
patients aged 20 to 80; patients with functional dyspepsia according to the ROME III criteria; patients in whom upper gastrointestinal endoscopy has not shown any organic causes of dyspepsia; patients without organic, systemic and metabolic diseases causing dyspepsia. Exclusion criteria: patients with peptic ulcer disease, inflammatory bowel disease, irritable bowel syndrome, pure gastro-esophageal reflux disease and any organic gastrointestinal disease; patients with a history of Helicobacter pylori infection eradicating drugs use within the past 3 months; patients with a history of gastrointestinal system surgery; patients with background systemic diseases such as diabetes mellitus, heart failure, hepatic failure, renal failure, asthma, chronic obstructive pulmonary disease, neoplasms and severe psychiatric diseases; patients addicted to alcohol and opium; patients using cardiac, antihypertensive, antipsychotic, antianxiety, antibiotic and corticosteroid drugs and iron and calcium; patients with a history of discontinuing prescribed pharmacotherapy and incomplete treatment; pregnant women; women planning pregnancy; breast-feeding women.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Dyspepsia. Timepoint: Before intervention and 2 months after intervention. Method of measurement: Hong Kong dyspepsia index questionnaire.
- Secondary Outcome Measures
Name Time Method Quality of life. Timepoint: Before intervention and 2 months after intervention. Method of measurement: SF-36 questionnaire.;Helicobacter pylori infection. Timepoint: Before intervention and 2 months after intervention. Method of measurement: Urease test.;Adverse drug reactions. Timepoint: Before intervention and 2 months after intervention. Method of measurement: Patient questioning.