CTRI/2018/10/015943
Completed
未知
COMPARATIVE STUDY TO ASSESS THE EFFICACY AND COSTEFFICIENCY OF IMMUNOLOGICALLY- TARGETED LOW DOSERITUXIMAB PROTOCOL WITH THE CONVENTIONALRHEUMATOID ARTHRITIS PROTOCOL IN SIGNIFICANT PEMPHIGUS
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Health Condition 1: L100- Pemphigus vulgarisHealth Condition 2: L100- Pemphigus vulgaris
- Sponsor
- DEPARTMENT OF DERMATOLOGY
- Enrollment
- 23
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •PATIENTS OF PEMPHIGUS VULGARIS OR PEMPHIGUS FOLIACEOUS IN THE ABOVE MENTIONED AGE GROUP WITH SIGNIFICANT CLINICAL DISEASE WITH PDAI( PEMPHIGUS DISEASE ACTIVITY INDEX) SCORE \>15 AND WHO ARE WILLING FOR MONTHLY FOLLOW UP VISITS FOR 12 MONTHS.
Exclusion Criteria
- •PATIENTS WITH ACTIVE OR LATENT INFECTIONS LIKE HEPATITIS, TB OR SEPSIS.PREGNANT AND LACTATING FEMALES, PATIENTS WITH KNOWN CARDIAC ABNORMALITIES OR ARRHYTHMIA, SEVERELY DECREASED BONE MARROW FUNCTIONS, KNOWN HYPERSENSITIVITY TO MURINE PROTEINS OR ORAL CORTICOSTEROIDS. PATIENTS WHO HAVE RECEIVED RITUXIMAB IN PRECEDING 12 MONTHS OR DEXAMETHASONE PULSE THERAPY IN PRECEDING 3 MONTHS WILL ALSO BE EXCLUDED.
Outcomes
Primary Outcomes
Not specified
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