Comparison of clindamycin - benzoyl peroxide versus adapalene - benzoyl peroxide in patients of acne

Phase 4

• Conditions: Health Condition 1: L700- Acne vulgaris

• Registration Number: CTRI/2019/04/018786
• Lead Sponsor: Government medical college Nagpur

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1) Subjects of either gender

2) Subjects of 12 to 35 years of age with mild to moderate (comedones, papules and few pustules) facial acne vulgaris having more than or equal to 2 and less than equal to 30 lesions(inflammatory and/or non inflammatory) lesions

Exclusion Criteria

1)Patients already on anti-acne medication in last one month

2) Patients having nodulocystic lesions, acne conglobata, acne fulminans, secondary acne

3) Patients unwilling to give written informed consent

4) Patients with known hypersensitivity to benzoyl peroxide, clindamycin or adapalene

5) Pregnant or lactating women

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the efficacy of clindamycin 1% -benzoyl peroxide 2.5% with adapalene 0.1% - benzoyl peroxide 2.5% in mild to moderate facial acne vulgaris by lesion counting.Timepoint: 4 weeks, 8 weeks and 12 weeks

Secondary Outcome Measures

Name	Time	Method
1)To compare the safety of clindamycin 1% -benzoyl peroxide 2.5% with adapalene 0.1% - benzoyl peroxide 2.5% in mild to moderate facial acne vulgaris by lesion counting by clinical examination on scale of 0 to 3. <br/ ><br>2)To compare the cost effectiveness of clindamycin 1% -benzoyl peroxide 2.5% with adapalene 0.1% - benzoyl peroxide 2.5% in mild to moderate facial acne vulgaris by lesion counting.Timepoint: 4, 6 and 12 weeks