Study of Intracameral Adrenaline for Pupil Dilation Without Topical Mydriatics in Refractive Cataract Surgery

Not Applicable

Completed

• Conditions: Cataract
• Interventions: Drug: adrenalin

• Registration Number: NCT01264653
• Lead Sponsor: Wenzhou Medical University

Brief Summary

The purpose of this study is to study the safety and efficacy of intracameral adrenaline for pupil dilation without topical mydriatics in refractive cataract surgery.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-12
• Study First Submitted: 2010-12-20
• Study First Submitted QC: 2010-12-21
• Study First Posted: 2010-12-22
• Primary Completion: 2011-12
• Study Completion: 2011-12
• Status Verified: 2012-07
• Last Update Submitted: 2012-07-04
• Last Update Posted: 2012-07-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• male and female
• can read and sign informed consent form；
• Clinical diagnosis of cataract
• Cataract density grade II-III according to the Emery-Little system classification system

Exclusion Criteria

• sensitivity to adrenalin；
• sensitivity to topical mydriatics；
• any other ocular surgeries；
• iris abnormalities

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
experimental group,control group	adrenalin	Intraocular adrenalin,topical mydriatics, experimental group: Intervention: Procedure:refractive cataract surgery with Intraocular adrenalin, control group:refractive cataract surgery with topical mydriatics

Primary Outcome Measures

Name	Time	Method
Pupil size after intracameral adrenaline	1day	We would like to evaluate Pupil size dilated with intracameral adrenaline 0.01%

Secondary Outcome Measures

Name	Time	Method
endothelial cell count	1month	we would like to evaluate the endothelial cell count 1 month after surgery

Trial Locations

Locations (1)

Wenzhou Medical College; 🇨🇳 Wenzhou, Zhejiang, China