Epinephrine

Generic Name
Epinephrine
Brand Names
Adrenalin, Allerject, Anapen, Articadent, Astracaine, Auvi-Q, Citanest, Citanest Forte, Emerade, Epipen, Lignospan, Marcaine, Marcaine With Epinephrine, Octocaine, Octocaine With Epinephrine, Orabloc, Scandonest, Sensorcaine, Sensorcaine With Epinephrine, Septanest, Septocaine, Symjepi, Ultacan, Ultracaine, Vivacaine, Xylocaine, Xylocaine With Epinephrine, Zorcaine, Eurneffy
Drug Type
Small Molecule
Chemical Formula
C9H13NO3
CAS Number
51-43-4
Unique Ingredient Identifier
YKH834O4BH
Background

Epinephrine, also known as adrenaline, is a hormone and neurotransmitter and produced by the adrenal glands that can also be used as a drug due to its various important functions. Though it has long been used in the treatment of hypersensitivity reactions, epinephrine in the auto-injector form (EpiPen) has been available since 1987 in the USA. Many new produ...

Indication

Epinephrine injection is indicated in the emergency treatment of type I allergic reactions, including anaphylaxis. It is also used to increase mean arterial blood pressure in adult patients with hypotension associated with septic shock.
...

Associated Conditions
Anaphylaxis, Angioneurotic Edema, Bleeding, Bronchospasm, Complete Heart Block, Hypotension, Idiopathic Anaphylaxis, Laryngotracheobronchitis, Mild Intermittent Asthma, Nasal Congestion, Open Angle Glaucoma (OAG), Respiratory Distress, Severe Asthma, Syncope, Type I Hypersensitivity, Urticaria, Uterine Contractions, Ventricular Fibrillation, Resuscitation in cardiac arrest following anesthetic accidents, Severe hypersensitivity reactions, Unresponsive Asystole, Unresponsive Bradycardia
Associated Therapies
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Epinephrine Vs Norepinephrine Infusion During Caesarean Delivery

Not Applicable
Not yet recruiting
Conditions
Interventions
First Posted Date
2024-07-22
Last Posted Date
2024-07-22
Lead Sponsor
Cairo University
Target Recruit Count
212
Registration Number
NCT06512402
Locations
🇪🇬

Cairo University, Cairo, Egypt

Multimodal Orthognathic Study Comparing Use of Exparel With Standard of Care.

First Posted Date
2024-07-12
Last Posted Date
2024-07-19
Lead Sponsor
United States Naval Medical Center, San Diego
Target Recruit Count
86
Registration Number
NCT06499181
Locations
🇺🇸

Naval Medical Center San Diego, San Diego, California, United States

Early Resuscitation in Paediatric Sepsis Using Inotropes

Phase 2
Not yet recruiting
Conditions
Interventions
First Posted Date
2024-06-27
Last Posted Date
2024-06-27
Lead Sponsor
NATALIA LOPERA MUNERA
Target Recruit Count
40
Registration Number
NCT06478797
Locations
🇦🇷

Hospital de Niños "Dr. Orlando Alassia", Santa Fe, Argentina

🇧🇴

Hospital Regional San Juan De Dios Tarija, Tarija, Bolivia

🇵🇾

Hospital De Clínicas, Asunción, Paraguay

and more 1 locations

Bupivacaine and Epinephrine Injection Study

First Posted Date
2024-06-13
Last Posted Date
2024-06-13
Lead Sponsor
Amin Javer
Target Recruit Count
80
Registration Number
NCT06456255

Intrathecal Dexmedetomidine vs Epinephrine

First Posted Date
2024-05-17
Last Posted Date
2024-10-11
Lead Sponsor
Icahn School of Medicine at Mount Sinai
Target Recruit Count
90
Registration Number
NCT06418308
Locations
🇺🇸

Mount Sinai Hospital, New York, New York, United States

Regional Lipolysis and Adipocyte Lipolysis Protein Stimulation

Early Phase 1
Recruiting
Conditions
Interventions
First Posted Date
2024-05-16
Last Posted Date
2024-12-05
Lead Sponsor
Mayo Clinic
Target Recruit Count
24
Registration Number
NCT06416969
Locations
🇺🇸

Mayo Clinic in Rochester, Rochester, Minnesota, United States

Liposomal Bupivacaine Use in Alveolar Bone Graft Patients

First Posted Date
2024-02-29
Last Posted Date
2024-07-03
Lead Sponsor
Kerry O'Rourke
Target Recruit Count
60
Registration Number
NCT06284434
Locations
🇺🇸

Shriners Children's Chicago, Chicago, Illinois, United States

Epinephrine in Irrigation Fluid for Visualization During Ankle Surgery

First Posted Date
2024-02-20
Last Posted Date
2024-10-14
Lead Sponsor
The Guthrie Clinic
Target Recruit Count
78
Registration Number
NCT06264596
Locations
🇺🇸

Robert Packer Hospital, Sayre, Pennsylvania, United States

Comparative Efficacy of Hypertonic Saline vs Adrenaline Nebulization in Acute Bronchiolitis

First Posted Date
2024-02-20
Last Posted Date
2024-08-22
Lead Sponsor
Combined Military Hospital, Pakistan
Target Recruit Count
60
Registration Number
NCT06267118
Locations
🇵🇰

Combined Military Hospital, Nowshera, KPK, Pakistan

Comparing the Efficiency of Two Approaches in Patients at Risk of Developing Intraoperative Floppy Iris Syndrome

First Posted Date
2024-02-20
Last Posted Date
2024-02-20
Lead Sponsor
University Hospital Olomouc
Target Recruit Count
164
Registration Number
NCT06266962
Locations
🇨🇿

Department of Ophthalmology, University Hospital Olomouc, Olomouc, Czechia

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