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Aquestive Therapeutics

Aquestive Therapeutics logo
🇺🇸United States
Ownership
Public
Established
2004-01-15
Employees
135
Market Cap
$421.6M
Website
http://www.aquestive.com
Introduction

Aquestive Therapeutics, Inc. engages in the identifying, developing, and commercializing differentiated products to address unmet medical needs and to solve patients’ therapeutic problems. Its product pipeline include Libervant, AQST-108, AQST-305, Suboxone and Zuplenz. The company was founded in January 2004 and is headquartered in Warren, NJ.

Clinical Trials

8

Active:0
Completed:6

Trial Phases

3 Phases

Phase 1:2
Phase 2:5
Phase 3:1

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (8 trials with phase data)• Click on a phase to view related trials

Phase 2
5 (62.5%)
Phase 1
2 (25.0%)
Phase 3
1 (12.5%)

Pharmacokinetics Study of DESF in Adults with Oral Allergy Syndrome

Phase 2
Completed
Conditions
Allergic Reaction
Interventions
First Posted Date
2024-07-30
Last Posted Date
2024-11-05
Lead Sponsor
Aquestive Therapeutics
Target Recruit Count
36
Registration Number
NCT06527937
Locations
🇺🇸

Frontage Clinical Services, Inc., Secaucus, New Jersey, United States

Diazepam Buccal Film (DBF) - Diastat Rectal Gel (DRG) Crossover Study

First Posted Date
2019-05-17
Last Posted Date
2020-08-18
Lead Sponsor
Aquestive Therapeutics
Target Recruit Count
31
Registration Number
NCT03953820
Locations
🇺🇸

Clinical Trials of Florida, LLC, Miami, Florida, United States

🇺🇸

Bioclinica Research, Orlando, Florida, United States

🇺🇸

Florida Premier Research Institute, LLC, Winter Park, Florida, United States

Riluzole Oral Soluble Film (ROSF) Swallowing Safety in Amyotrophic Lateral Sclerosis (ALS)

Phase 2
Terminated
Conditions
Amyotrophic Lateral Sclerosis
Interventions
First Posted Date
2018-09-21
Last Posted Date
2020-08-18
Lead Sponsor
Aquestive Therapeutics
Target Recruit Count
9
Registration Number
NCT03679975
Locations
🇺🇸

University of Florida Center for Movement Disorders & Neuroscience, Gainesville, Florida, United States

Riluzole Oral Soluble Film Safety and Tolerability in Amyotrophic Lateral Sclerosis

Phase 2
Withdrawn
Conditions
ALS
Interventions
First Posted Date
2018-03-08
Last Posted Date
2019-05-13
Lead Sponsor
Aquestive Therapeutics
Registration Number
NCT03457753
Locations
🇺🇸

Texas Neurology, P.A., Dallas, Texas, United States

Safety and Tolerability Study of Diazepam Buccal Film (DBF) in Subjects With Epilepsy

First Posted Date
2018-02-09
Last Posted Date
2021-08-05
Lead Sponsor
Aquestive Therapeutics
Target Recruit Count
149
Registration Number
NCT03428360
Locations
🇺🇸

Hawaii Neuroscience Center, Honolulu, Hawaii, United States

🇺🇸

Consultants in Epilepsy and Neurology, PLLC, Boise, Idaho, United States

🇺🇸

Clinical Research Center of New Jersey (CRCNJ), Voorhees, New Jersey, United States

and more 3 locations
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News

Aquestive Therapeutics Receives FDA Approval for Anaphylm New Drug Application, Targeting $2 Billion Severe Allergic Reaction Market

The U.S. Food and Drug Administration has approved Aquestive Therapeutics' New Drug Application for Anaphylm, a sublingual epinephrine product for treating severe allergic reactions.

Anaphylm Shows Consistent Efficacy Despite Oral Allergy Syndrome Complications

Phase 2 trial demonstrates that Anaphylm maintains its pharmacokinetic and pharmacodynamic profiles in patients with Oral Allergy Syndrome, showing comparable or superior effectiveness to intramuscular epinephrine.

Aquestive Therapeutics Advances Anaphylm NDA Submission and Alopecia Areata Trial

Aquestive Therapeutics is on track to submit its NDA for Anaphylm sublingual film in Q1 2025, aiming to provide the first orally delivered epinephrine for severe allergic reactions.

Aquestive and Insignis Advance Needle-Free Epinephrine Options for Anaphylaxis Treatment

Aquestive Therapeutics' Anaphylm sublingual film receives positive FDA feedback, reaffirming the NDA submission guidance for Q1 2025, potentially becoming the first orally delivered epinephrine product.

Aquestive Therapeutics Advances Anaphylm and AQST-108, Reports Q3 2024 Financial Results

Aquestive Therapeutics plans to submit Anaphylm™ (epinephrine) Sublingual Film for FDA approval after completing adult supportive studies, with a pre-NDA meeting scheduled for Q4 2024.

Aquestive's Epinephrine Film Demonstrates Rapid Relief for Oral Allergy Syndrome

Aquestive Therapeutics' Anaphylm, a sublingual epinephrine film, shows symptom relief for oral allergy syndrome (OAS) within two minutes.

Aquestive's Anaphylm Shows Rapid Symptom Resolution in Oral Allergy Syndrome Study

Aquestive Therapeutics' Anaphylm sublingual film met both primary and secondary endpoints in an Oral Allergy Syndrome (OAS) challenge study.

Aquestive's Anaphylm Sublingual Film Shows Rapid Symptom Resolution in Allergy Challenge Study

Aquestive Therapeutics' Anaphylm sublingual film demonstrated rapid resolution of allergen-related symptoms, beginning within 2 minutes of administration in an Oral Allergy Syndrome (OAS) challenge study.

Aquestive's Sublingual Epinephrine Film, Anaphylm, Nears NDA Submission for Anaphylaxis Treatment

Aquestive Therapeutics anticipates submitting a New Drug Application (NDA) for Anaphylm, a sublingual epinephrine film, to the FDA in the first quarter of 2025.

Aquestive Therapeutics Advances Anaphylm and Alopecia Treatment, Receives Analyst Boost

Aquestive Therapeutics' Anaphylm sublingual film demonstrated rapid symptom resolution in an oral allergy syndrome challenge study, with a median time of 12 minutes.

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