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The effect of capsular extract of Morus Alba leaves on nephropathic complications of diabetes mellitus type 2

Phase 2
Conditions
Diabetic Nephropathy.
Non-insulin-dependent diabetes mellitus with renal complications
Registration Number
IRCT2016021512438N18
Lead Sponsor
Barij Research Center of Medicinal Herbs
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
70
Inclusion Criteria

inclusion criteria: patients 35 to 70 years old receiving reducer blood glucose drug and dietary recommendations for 3 to 5 years with type II diabetes. That LDL-cholesterol less than 130 and triglycerides less than 300.
Exclusion criteria: liver disease, allergies to plants used in the clinical trial, changing the dose of drug during the study.

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Fasting plasma glucose. Timepoint: Baseline and End-of-tria. Method of measurement: blood sample.;Lipid profile. Timepoint: Baseline and End-of-tria. Method of measurement: blood sample.;Insulin. Timepoint: Baseline and End-of-tria. Method of measurement: blood sample.;Total anti oxidant capacity(TAC). Timepoint: Baseline and End-of-tria. Method of measurement: blood sample.;Alanine aminotransferase(ALT), Aspartate aminotransferase(AST). Timepoint: Baseline and End-of-tria. Method of measurement: blood sample.;Hs-CRP. Timepoint: Baseline and End-of-tria. Method of measurement: blood sample.;Blood urea nitrogen. Timepoint: Baseline and End-of-tria. Method of measurement: urine sample.;CREATININ. Timepoint: Baseline and End-of-tria. Method of measurement: urine sample.;PRO. Timepoint: Baseline and End-of-tria. Method of measurement: urine sample.;HbA1C. Timepoint: Baseline and End-of-tria. Method of measurement: percent of glycosylated hemoglobin.
Secondary Outcome Measures
NameTimeMethod
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