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临床试验/CTRI/2026/04/109438
CTRI/2026/04/109438尚未招募4 期

A prospective comparative randomised study to evaluate the effectiveness of oral clonidine vs oral pregabalin in attenuating the hemodynamic pressor response during laryngoscopy and tracheal intubation

D Y Patil Hospital1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2026年5月20日最近更新:

试验速览

阶段
4 期
状态
尚未招募
入组人数
40
试验地点
1

研究概览

简要总结

Study drugs will be given 120 minutes prior to operation then Routine General Anaesthesia will be given, the hemodynamic pressor response to laryngoscopy and tracheal intubation is common and technique to reduce this response by drugs is a routine practice, study will compare two drugs Clonidine and pregabalin used for attenuation of hemodynamic response during laryngoscopy and tracheal intubation.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • Patients belonging to ASA grade I, II.
  • Anticipated duration of surgery between 2-4 hours.
  • Patient consenting for the trial drug.

排除标准

  • Patients with anticipated difficult intubation.
  • Patients with High risk of aspirations.
  • History of Neurologic or seizure disorder.
  • Hypersensitivity to the drugs.
  • Patients on beta blockers.
  • Emergency surgeries.

研究者

申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Manjula Sarkar

D Y Patil Hospital

研究点 (1)

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