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临床试验/NCT05343247
NCT05343247已完成不适用

Evaluation of Dental Age of Children With Amelogenesis Imperfecta Using Cameriere European Formula and London Atlas

Istanbul University1 个研究点 分布在 1 个国家目标入组 416 人开始时间: 2022年3月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
416
试验地点
1
主要终点
Correlation coefficient of Cameriere European formula.

研究概览

简要总结

The aim of this study is to investigate whether there is a significant difference in dental age between children with amelogenesis imperfecta (AI) and healthy controls using Cameriere European formula and London Atlas. If there is a significant difference in dental age between children with AI and healthy controls, it is aimed to create a new formula.

详细描述

One of the developmental enamel defects, amelogenesis imperfecta (AI), is also known as enamel hypoplasia/hypomineralization. It is a rare inherited disease that affects the enamel structure, amount and component in primary and permanent teeth, and it has been reported to be accompanied by some dental anomalies and nephrocalcinosis. Dental anomalies and nephrocalcinosis can affect tooth development, and there are limited studies examining tooth development in these individuals.Dental age is widely evaluated by pedodontists, forensic dentists and orthodontists. While a delay in tooth development may be associated with growth retardation and learning difficulties, dental age determination can also be used for forensic age determination for children whose birth information is uncertain. A clear assessment of maturation in children with continued growth is important in establishing a dental treatment plan.

Dental age is widely evaluated by pedodontists, forensic dentists and orthodontists. While a delay in tooth development may be associated with growth retardation and learning difficulties, dental age determination can also be used for forensic age determination for children whose birth information is uncertain. A clear assessment of maturation in children with continued growth is important in establishing a dental treatment plan.

There are two basic approaches to dental age determination in children:

  1. evaluation of eruption of teeth in the oral cavity,
  2. evaluation of the development and mineralization of crowns and roots on dental radiographs.

In many methods, the developmental stages of different numbers of permanent teeth are used.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

年龄范围
5 Years 至 13 Years(Child)
性别
All
接受健康志愿者

入选标准

  • 5-13 years old
  • Healthy children
  • Children with AI
  • Patients without missing left mandibular permanent teeth on panoramic radiography

排除标准

  • Children older than 5 years old and younger than 14 years (children that cannot be assessed by the Willems and Cameriere method)
  • Poor quality panoramic radiography
  • Patients who have received orthodontic treatment
  • Patients who received restorative or endodontic treatment

结局指标

主要结局

Correlation coefficient of Cameriere European formula.

时间窗: day 1

Dental age of children with AI and healthy controls assessed by the correlation coefficient.

Correlation coefficient of London Atlas method.

时间窗: day 1

Dental age of children with AI and healthy controls assessed by the correlation coefficient.

次要结局

  • Dental age estimation in children with AI(day 1)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Yelda Kasımoğlu

Principal investigator

Istanbul University

研究点 (1)

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