ISRCTN31345163
Completed
N/A
GENetic and clinical Predictors Of treatment response in Depressio
Medical Research Council (UK)0 sites887 target enrollmentSeptember 19, 2003
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Medical Research Council (UK)
- Enrollment
- 887
- Status
- Completed
- Last Updated
- 11 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •18\-74 years with the more severe depressions in whom the GP and patient have already agreed that antidepressants should be prescribed. We will therefore only include those with a Clinical Interview Schedule \- Revised (CIS\-R) score of \=20, a Beck Depression Inventory (BDI) score of \=15 and a diagnosis of International Statistical Classification of Diseases and Related Health Problems, tenth revision (ICD\-10\) depressive episode F32 and F33 (from CIS\-R).
Exclusion Criteria
- •Pregnant and breast feeding women, patients with psychotic illness, alchohol or substance abuse problems, patients with medical contraindications to Citalopram or Reboxetine. (June 2006: Exclusion criteria were provided as follows: Potential subjects who have taken antidepressant medication within 2 weeks, who cannot complete self\-administered scales, who have a psychosis or major substance or alcohol abuse. The GP will exclude anyone who has medical contraindications or in whom participation in the trial is not appropriate.)
Outcomes
Primary Outcomes
Not specified
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