Non-invasive Evaluation of the Predictive Value of CEUS and SWE in Patients With and Without TIPS With ACLF, Renal Failure and Hepatorenal Syndrome
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- Survival
研究概览
简要总结
Evaluation of non-invasive prognostic parameters in patients developing ACLF and renal failure in patients receiving and not receiving transjugular intrahepatic portosystemic shunt (TIPS). Patients are cared according to the local standardized follow up program. Clinical and laboratory data from standard patient care are evaluated for potential prognostic value.
详细描述
NECTAR consists of patients with ACLF and renal failure with and without receiving transjugular intrahepatic portosystemic shunt (TIPS) at the Department of Internal Medicine I, University of Bonn, Germany and receiving a structured routine evaluation and follow up program. The diagnosis of cirrhosis was based on clinical, hemodynamic and biochemical parameters, and ultrasound and/or biopsy criteria.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients with portal hypertension and kidney failure
排除标准
- •no consent, no kidney failure, no portal hypertension
结局指标
主要结局
Survival
时间窗: up to 10 years
death, liver transplantation
次要结局
- Organ Failures(up to 10 years)
- Hepatic Encephalopathy(up to 10 years)
- Ascites(up to 10 years)
- Acute-on-Chronic Liver Failure(up to 10 years)
- Liver Failure(up to 10 years)
- Kidney Failure(up to 10 years)
- Variceal Bleeding(up to 10 years)
研究者
Michael Praktiknjo
MD
University Hospital, Bonn