RAndomised controlled trial to imProve depressIon and the quality of life of people with Dementia using cognitive bias modification (RAPID)

Not Applicable

• Conditions: depression; Alzheimer's disease; Neurological - Alzheimer's disease; Mental Health - Depression

• Registration Number: ACTRN12614000420640
• Lead Sponsor: WA Centre for Health & Ageing

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-04-16
• Study Completion: 2016-09-29
• Last Update Posted: 16 February 2021

Recruitment & Eligibility

• Status: Stopped early
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

We will recruit 80 people with depression in mild to moderate severity Alzheimer’s disease according to the following inclusion criteria:
1.Diagnosis of probable AD according to NINCDS-ADRDA criteria, which is largely consistent with DSM-V diagnosis of major neurocognitive disorder due to probable AD,
2.Mini-Mental State Examination (MMSE) score equal or greater than 15,
3.Cornell Scale for Depression in Dementia (CSDD) equal or greater than 8,
4.Fluent in written and spoken English (preferred language for at least 10 years).

Exclusion Criteria

We will exclude from participation people who have:
1.One or more diseases likely to compromise ongoing participation in the trial (for example, severe visual impairment),
2.A weekly alcohol consumption greater than 28 standard drinks (> 4 drinks per day) or 6 or more standard drinks on any one day of the week,
3.Active suicidal intent,
4.No health practitioner who is able to provide ongoing clinical care,
5.Changed antidepressants during the preceding four weeks,
6.Not given informed consent to participate.

Study & Design

• Study Type: Interventional
• Study Design: Not specified