Effect of Home-Based Transcranial Direct Current Stimulation (tDCS) on Cognitive Functio

Not Applicable

• Conditions: Mental and behavioral disorders

• Registration Number: KCT0002721
• Lead Sponsor: Yonsei University Health System, Severance Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 11 March 2019

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

1) Adults with the age of 60 or more, but less than 80 (based on resident registration number)
2) Those with subjective memory impairment while maintaining normal general functions and daily life performance
3) Declined cognitive function suggested by Korean Version of the Mini–Mental State Examination for Dementia Screening(MMSE-DS)
4) Seoul-Instrumental Activities of Daily living score 7 or below
5) Korean version of Global Deterioration Scale (GDS) score of 2~3 or Clinical Dementia Rating(CDR) score of 0.5 assessed by the clinician
6) Korean version of Geriatric depression scale(K-GDS) score 8 or below

Exclusion Criteria

1) A person who was diagnosed with the Alzheimer's disease or is currently taking cognitive enhancer such as donepezil, rivastigmine, galantamine, or memantine
2) History of intellectual disability
3) Medical history that can cause cognitive dysfunction
4) A person who is currently diagnosed with alcohol dependence using Diagnostic and Statistical Manual of Mental Disorders 4th edition(DSM-IV)
5) History of seizure
6) A person who suffers from serious dysfunction in cardiovascular, digestive, respiratory, endocrine or central nervous systems
7) A person who received cerebrovascular surgery including brain and carotid artery
8) A person who seems to have a problem with attaching the electrodes due to scalp deformity, inflammatory reaction, or other dermatological reasons
9) A person who is prohibited from applying transcranial direct current stimulation device with other reasons such as a metal plate inserted in cephalic region
10) A person who participated in other clinical trials within 30 days from screening
11) A person who wears glasses, but still are unable to read the ordinary writings because of the visual problem
12) A person who uses the hearing aid, but still has difficulty in understanding the conversation because of the auditory problem
13) Apart from as mentioned above, person with any disqualifying clinical problem determined by the investigator
* Patients who take medication for psychiatric treatment or internal disease treatment can be included

Study & Design

• Study Type: Interventional Study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
visual recognition task

Secondary Outcome Measures

Name	Time	Method
etter- Number Sequencing;Spatial Span;Clinical Global Impression;Neuropsychiatric Inventory;The Korean version of the Consortium to Establish a Registry for Alzheimer’s Disease Neuropsychological Assessment Battery