Effect of dexmedetomidine infusion on N-terminal pro-B-type natriuretic peptide level
Phase 2
- Conditions
- Fracture of femural shaft.Fracture of shaft of femur
- Registration Number
- IRCT201511279593N2
- Lead Sponsor
- ?Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Patients with femoral shaft fracture who were candidates for elective surgery under general anesthesia; between 15 and 55 years; ASA Class I, II
Exclusion criteria: positive history of any cardiac or hepatic problem; addiction to any specific drug; using anti hypertensive, psychiatric, agonist or antagonist a-2 receptor agents; basal heart rate less than 60/min; pregnant patient; patients who had blood loss of more than 1 liter during surgery; patients for whom the time of operation took more than 3 hours
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method T pro BNP. Timepoint: before induction and 24 hours after surgry. Method of measurement: blood level.
- Secondary Outcome Measures
Name Time Method Systolic blood pressure. Timepoint: every 30 min from induction until end of surgry. Method of measurement: based on mmHg.;Diastolic blood pressure. Timepoint: every 30 min from induction until end of surgry. Method of measurement: based on mmHg.;Pulse rate. Timepoint: every 30 min from induction until end of surgry. Method of measurement: per minute.