Phase III randomized clinical trial of elective neck irradiation in oropharyngeal squamous cell cancer: Is high dose necessary?
Phase 3
Recruiting
- Conditions
- Oropharyngeal squamous cell cancer
- Registration Number
- TCTR20180203001
- Lead Sponsor
- Faculty of Medicine, Chulalongkorn University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 180
Inclusion Criteria
-Stage I-IVB oropharyngeal cancer
-Adequate performance status
-Anticipated to the informed consent
Exclusion Criteria
-Evidence of distant metastasis
-Recurrent oropharyngeal cancer
-Undergone surgery upon primary tumor or neck apart from incisional or excisional biopsy
-Previous irradiation for head neck tumor
-Prior chemotherapy to study entry
-History of malignancy other than non-melanoma skin cancer which is controlled at least 5 years
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ocoregional control 2 years Rate of recurrence in elective neck area
- Secondary Outcome Measures
Name Time Method Acute toxicities During radiation treatment CTCAE 4.03,Late toxicities 2 years CTCAE 4.03