Ventilatory setting in patients undergoing robot assisted prostate surgery using transpulmonary pressure for titrating optimal PEEP.
- Conditions
- Participants in this study will be the patients who fulfill the following criteria. 1.The patients who have prostatic cancer and will have elective robot-assisted surgery. 2.The age does not matter. 3.The patients with the risk 1 or 2 of the ASA(American Society of Anesthesiologist) . 4.The BMI of the patients is less than 35 5.The patients with NYHA1 and Hugh-Jones1 6.The patients who can sign a consent form to participate this study
- Registration Number
- JPRN-UMIN000036376
- Lead Sponsor
- Tokyo Medical University Hospital
- Brief Summary
The median PEEP level associated with PtpEEP0 was 15 cmH2O. Respiratory system compliance values were higher at PtpEEP0 than those at PEEP5 (P = 0.02). Driving pressure was lower at PtpEEP0 than at PEEP5 (P=0.0036). The cardiac index remained unchanged, and the values of rSO2 were higher at PtpEEP0 than at PEEP0 (right; P=0.0019, left; P=0.036).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Male
- Target Recruitment
- 14
Not provided
1.The past history of a disorder of the central nervous system 2.The past of the thoracic operation. 3.The past of the myocardial infarction or heart failure 4.Problem with insertion in the esophagus.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.transpulmonary pressure 2.airway pressure(peak airway pressure,inspiratory plateau pressure,mean airway pressure,PEEP) 3.esophageal pressure(peak,mean,end-expiratory) 4.P/F ratio
- Secondary Outcome Measures
Name Time Method 1.hart rate,arterial pressure 2.SpO2, ORI oxygen reserve index 3.arterial blood gas 4.lung thorax compliance 5.cerebral oxygen saturation:rSO2 6.Vigileo monitor Cardiac Output, Stroke Volume Stroke Volume Variation