NCT00730938已完成不适用
The Effect of Intracameral Cefuroxime on Post-op Fibrin in Pediatric Cataract Surgery
Presbyterian Church East Africa Kikuyu Hospital1 个研究点 分布在 1 个国家目标入组 45 人开始时间: 2008年2月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 45
- 试验地点
- 1
- 主要终点
- Fibrin formation in anterior chamber
研究概览
简要总结
The study investigates whether placing an antibiotic inside the eye at the end of cataract surgery in children will reduce the amount of fibrin formation (fibrin formation can block the pupil and reduce vision). We hypothesize that the fibrin is caused by a low-level infection and could be prevented by the antibiotic.
详细描述
The study investigates whether using an antibiotic (cefuroxime) in the anterior chamber of the eye at the end of surgery for cataract in children will reduce the amount of fibrin formation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 6 Months 至 15 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •bilateral congenital or developmental pediatric cataract
排除标准
- •traumatic cataract
研究组 & 干预措施
1
Active Comparator
干预措施: cefuroxime (Drug)
2
Placebo Comparator
Saline placebo
干预措施: Saline placebo (Drug)
结局指标
主要结局
Fibrin formation in anterior chamber
时间窗: 4th postoperative day
次要结局
未报告次要终点
研究者
研究点 (1)
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