Comparison of add on drugs Dexmedetomidine and Fentanyl to Ropivacaine in pregnant patients undergoing cesarean sectio

Not Applicable

• Conditions: Health Condition 1: O00-O9A- Pregnancy, childbirth and the puerperium

• Registration Number: CTRI/2021/02/031038
• Lead Sponsor: Dr Ashna Shetty

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1.Parturients of age group 18-35 years undergoing elective lower segment caesarean section under subarachnoid block.

2.Parturients willing to give written informed consent[annexure 1(a)]

3.Parturients belonging to ASA II[annexure 3(a)]

Exclusion Criteria

1.Patients undergoing emergency lower segment caesarean section under subarachnoid block

2.Patients with medical and obstetric complications like anaemia , heart diseases , gestational hypertension, gestational diabetes , shock, septicaemia and hypertension

3.Patients not willing to give consent .

4. Patients with history of hypersensitivity to local anaesthetic, Dexmedetomidine , Fentanyl

5.Subjects having any absolute contraindications for spinal anaesthesia like increased ICP, severe hypovolemia , bleeding diathesis , local infection

6. Patients with height < 150cm and >170 cm and BMI >30

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.Sensory blockade with respect to onset , maximum level attained , time taken for attainment of maximum level , time taken for two segments sensory regression and total duration of sensory blockade <br/ ><br>2.Motor blockade with respect to onset , maximum level , time taken for attainment of maximum level, quality of motor blockade and total duration of motor blockade <br/ ><br>3.Total duration of analgesia <br/ ><br>Timepoint: 4 hours

Secondary Outcome Measures

Name	Time	Method
4.Neonatal APGAR scores <br/ ><br>5.Adverse effects like nausea , vomiting , desaturation, hypotension ,bradycardia and excessive sedation.Timepoint: 60 minutes