Comparison between two different drug namely Dexmedetomidine and Buprenorphine for efficacy and analgesia when given as a additive to spinal anaesthesia
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2024/03/063937
- Lead Sponsor
- Indira Gandhi Institute of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA physical status I & II
Age- 18-60 years
Sex- both male and female
Patients undergoing elective infra umbilical surgery under spinal anaesthesia
Exclusion Criteria
? Patients with known contraindication for spinal anaesthesia.
Patients with coagulation disorders or on anticoagulation therapy.
Patients with cardiac disease, nuerological.hepatc and renal impairment.
Patients with betablockers & alpha antagonists.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method two group has been taken <br/ ><br>group B will receive 0.75% isobaric ropivacaine 3ml with 60 mcg of buprenorphine in spinal anaesthesia. <br/ ><br>Group D will receive 0.75% isobaric ropivacaine 3ml with 5 mcg of dexmedetomidine in spinal anaesthesia.we will compare the effects on spinal block, time for rescue analgesia, and adverse effectsTimepoint: Vital sign will be recorded at every 10 minutes in operation theatre and every 15 minutes in post anaesthesia care unit
- Secondary Outcome Measures
Name Time Method 1) Time of onset of sensory and motor block <br/ ><br>2)Duration of sensory and motor block. <br/ ><br>3) Duration of postoperative analgesia . <br/ ><br>4) Peroperative and postoperative hemodynamic changes and side effectsTimepoint: 1.To estimate the time of onset of sensory and motor block at every 5 minutes <br/ ><br>2.To compare the duration of sensory and motor block at every 30 minutes <br/ ><br>3.To assess the duration of postoperative analgesia obtained in both groups at every 30 minutes <br/ ><br>4.To describe peroperative and postoperative hemodynamic changes and side effects at every 15 minutes <br/ ><br>